Associated Conditions & Findings
Lissencephaly
Lissencephaly is a malformation where the brain's surface is abnormally smooth, with too few folds.
In short: Lissencephaly
- It is a type of cortical malformation.
- It can be associated with certain syndromes.
- It can significantly affect development.
- It is identified on brain imaging.
What it is
It is a malformation of cortical development in which the brain's surface is abnormally smooth, lacking its normal folds. The name means "smooth brain."
Understanding Lissencephaly
It can be associated with certain syndromes (such as Walker-Warburg syndrome) and can significantly affect development. As a cortical malformation, lissencephaly reflects altered brain development that imaging characterizes; its presence is one of the more serious associated findings, and the team discusses its implications honestly with the family.
Why it matters
Understanding lissencephaly helps families see why imaging examines the brain's folding pattern and why certain syndromes are considered when this finding is present.
Common questions
What is lissencephaly?
A malformation with an abnormally smooth brain surface.
Can it be part of a syndrome?
Yes, such as Walker-Warburg syndrome.
How is it found?
On brain imaging.
Bottom line
Lissencephaly is an abnormally smooth brain surface that can accompany certain syndromes and significantly affect development.
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