Causes, Risk Factors & Associated Conditions
Marfan syndrome
Marfan syndrome is an inherited connective-tissue disorder that can be associated with Chiari malformation among its many features.
In short: Marfan syndrome
- It is an inherited connective-tissue disorder.
- It affects the skeleton, eyes, heart, and blood vessels.
- It can be associated with Chiari malformation.
- It is one of the syndromes linked to Chiari.
What it is
Marfan syndrome is an inherited connective-tissue disorder affecting multiple body systems — including the skeleton, eyes, heart, and blood vessels. Among its many features, it can be associated with Chiari malformation.
Understanding Marfan syndrome
Marfan syndrome results from changes in connective tissue and is known for features such as tall stature, long limbs, joint flexibility, eye problems, and cardiovascular issues (which require careful monitoring). Because it affects connective tissue and skeletal development, Marfan syndrome is among the conditions associated with Chiari malformation and related craniocervical features. When Chiari occurs in a person with Marfan syndrome, care is coordinated with management of the syndrome's other (sometimes more pressing) features, particularly cardiovascular ones. Recognizing Marfan syndrome as an associated condition helps ensure comprehensive evaluation. Understanding Marfan syndrome and Chiari clarifies one of the syndromes linked to the condition and the importance of coordinated care.
Why it matters
Understanding Marfan syndrome and Chiari helps families see that this connective-tissue disorder is among those associated with Chiari, and why care is coordinated with the syndrome's other features, especially cardiovascular ones.
Common questions
What is Marfan syndrome?
An inherited connective-tissue disorder affecting multiple body systems.
How does it relate to Chiari?
It can be associated with Chiari malformation.
Why coordinate care?
Marfan has other features, especially cardiovascular ones, that need management.
Bottom line
Marfan syndrome is an inherited connective-tissue disorder that can be associated with Chiari, requiring care coordinated with its other features.
Browse all 265 Chiari malformation definitions
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