Associated Conditions & Findings
Holoprosencephaly
Holoprosencephaly is a condition where the brain does not fully divide into two halves during development.
In short: Holoprosencephaly
- It can be associated with midline facial and brain differences.
- It is a disorder of early brain division.
- It can co-occur with certain syndromes.
- It is identified on brain imaging.
What it is
It is a condition in which the forebrain does not fully divide into two halves (hemispheres) during early development. Its severity ranges widely, from mild to significant.
Understanding Holoprosencephaly
It can be associated with midline facial and brain differences and can co-occur with certain genetic conditions, some of which are also relevant to encephalocele. Because it involves early brain division along the midline, it is part of the broader picture of midline brain development that imaging examines, and it can occur with a range of associated findings.
Why it matters
Understanding holoprosencephaly helps families see why midline brain development is examined and why certain genetic conditions are considered when midline brain and facial differences are present.
Common questions
What is holoprosencephaly?
Incomplete division of the brain into two halves.
What can it be associated with?
Midline facial and brain differences, and certain syndromes.
How is it found?
On brain imaging.
Bottom line
Holoprosencephaly is incomplete division of the brain into halves, associated with midline differences and certain syndromes.
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