Each AURORA module is a full disease vertical — registries, models, clinical workflows, ethics review and a path from bench to bedside. Five are in active build today; four more are specified and queued. Click any card for the full module page.
29 subsystems live or in build across glioma, hydrocephalus, encephalocele, craniosynostosis and Chiari malformation.
End-to-end stack for the most lethal primary brain tumor.
CSF dynamics, shunt logic and lifetime compartment care.
Prismatic anatomy and a forge for personalised closure.
Skull mechanics, biomarkers and neurodevelopmental endpoints.
From tonsillar position to whole-craniospinal hydrodynamics.
Spina bifida, tethered cord, Dandy-Walker malformation and arachnoid cysts. Specs are drafted and the clinical case is made — 15 subsystems planned — but build has not started. These are the diseases we take on next.
From prenatal closure to lifelong functional protection.
Mechanotransduction and release for a misunderstood syndrome.
Posterior fossa malformation, decoded across the lifespan.
From membrane origin to fluid-mechanics-aware fenestration.
Every subsystem is independently usable, with its own model card, eval and one-command install. Subsystems in planned modules carry the planned status until their module enters build.
Multi-omic systems map of glial lineages, niches and signalling.
Connects scanner-scale imaging with cell-scale histology features.
Immune-stromal-vascular crosstalk simulator with spatial priors.
Pre-trained vision-language-omics transformer for glioma.
Diffusion-reaction PDE solver for invasive margins beyond contrast.
Counterfactual graphs over treatment, resection and progression.
WHO-aligned molecular + histo + radio diagnostic synthesizer.
Auto-contoured GTV/CTV/PTV with dose-response priors.
Eligibility matcher and adaptive arm allocator for active studies.
Bias, consent and equity audit layer with provenance reports.
Patient-derived organoid digital twin synced with bench data.
CSF production, absorption and pulsatile transmantle pressure model.
Shunt vs. ETV decision support with personalised flow priors.
Lifetime shunt surveillance, infection and revision forecasting.
Voxel-precise atlas of frontoethmoidal, parietal and occipital subtypes.
Generative closure planning with patient-specific implants and grafts.
Cranial neural crest, suture stem cells and fusion biology.
Finite-element growth model of the constrained vault.
Imaging, fluid and genomic markers of severity and recurrence.
Photo + 3D scan diagnostic pipeline for early identification.
Spring-assisted, endoscopic and remodelling plan synthesiser.
Cognitive, language and behavioral trajectory modelling.
Open benchmarks across morphometry, planning and outcomes.
Validated composite endpoints for craniosynostosis trials.
Posterior-fossa morphometry: tonsillar position, clivus and supraocciput angles, foramen-magnum geometry, peg-like vs rounded tonsils.
Cine-MRI flow analysis at the foramen magnum; peak systolic velocity, dwell time, regurgitation, phase relationships.
Per-vertebral-level cord-cavity segmentation; syrinx morphology, expansion rate, longitudinal stability index.
Patient-specific risk model for posterior-fossa decompression with or without duraplasty; symptom-driven thresholds explicit.
Re-tonsillation, syrinx-recurrence and post-op pseudo-meningocele watch over years.
Neural tube closure simulator with folate-axis perturbations.
Imaging, lesion-level and timing decisions for in-utero repair.
MOMS-aligned planning for open and fetoscopic closures.
Long-term shunt, cord and skin protection over the lifespan.
Continence, ambulation, cognition and quality-of-life modelling.
Open hypotheses, registry signals and replication tracker.
Stretch-evoked axonal ion-flux and metabolic deficit modelling.
Occult vs. classical TCS clustering across paediatric and adult cohorts.
Risk-adjusted decision support for de-tethering surgery.
Post-op tracking and re-tether early-warning indicators.
Cerebellar vermis dysgenesis and 4th-ventricle cystic biology.
Long-horizon flow, behavior and cognitive trajectory simulator.
Arachnoid splitting biology and developmental staging.
Intra-cyst pressure, slit-flow and mass-effect simulator.
Comparative endoscopic vs. open fenestration planning.