Modules Module 01 of 09 Live

Glioma Gliomata

AURORA-GLIO

End-to-end stack for the most lethal primary brain tumor.

Glioblastoma and lower-grade gliomas remain the deadliest primary brain cancers. AURORA-GLIO unifies molecular profiling, radiomics, surgical planning, ethics and clinical translation into a single auditable, open pipeline.

Scope Adult & paediatric · WHO 2021 aligned
Readiness Spec frozen · prototypes building
Pilots 3 pilot sites scoping
Latency target target <150ms
License MIT
Build tally 7 live 3 beta 1 soon
01 · The clinical problem

Why this module exists.

Glioma is the most common malignant primary brain tumor in adults. Median survival in glioblastoma sits around 15 months despite four decades of trials. Heterogeneity — across patients and inside a single tumor — is the central problem AURORA-GLIO is built to address.

Built with and for
Neuro-oncology surgeons Radiologists Computational biologists Trialists
What this module is for

Research infrastructure that a named team can run inside its own perimeter, on research cohorts, and hand to the next team as a specification with running code.

Nothing in it diagnoses, triages, or produces output a clinician is expected to act on for an individual patient.

02 · Subsystems · 11 in AURORA-GLIO

Eleven vertical slices, one specification each.

Each subsystem is a slice of the module with its own specification. Pick one to see what it does and how far it has been built. Module readiness overall: “Spec frozen · prototypes building”.

Each square is one subsystem, shaded by build state against its specification. Not evaluation results, not regulatory status.
03 · For patients and families

The same condition, written for the people living with it.

50 plain-language guides and 265 defined terms, with no methodology and no jargon left unexplained.

04 · Evidence and oversight

Four gates before any clinical use, and each can send it back.

No AURORA module has entered this pathway. Every gate below reads not started, and will continue to until a real result is published and the site that produced it has agreed to be named. Build progress on the subsystems above is not evidence of clinical validity.

Gate 1Not started

Retrospective validation

Held-out data from sites that took no part in development.

Gate 2Not started

Silent prospective

Runs alongside standard care with no output shown to clinicians.

Gate 3Not started

Supervised clinical evaluation

Prospective, under ethics approval, reported to DECIDE-AI.

Gate 4Not started

Post-market monitoring

Continuous performance and drift tracking; degradation withdraws the module.

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