Patient-derived organoid digital twin synced with bench data.
Patient-derived organoid digital twin synced with bench data.
GLIO-ORG is one of 11 subsystems that compose AURORA-GLIO. It is independently usable but shares the same patient representation, provenance log and governance layer as every other AURORA module.
GLIO-ORG is the long-horizon bet. A patient-derived organoid is one of the few experimental systems that captures glioblastoma biology with any fidelity; the digital-twin layer keeps a representation of the organoid in sync with bench data and uses it as a sandbox for counterfactual exploration.
It is the furthest from clinical surfaces and the closest to research workflows. The pilot phase is bench-first. The module will ship a research-grade build at public alpha; a clinic-grade build is a later milestone.
GLIO-ORG can be installed standalone, or pulled in as part of the full AURORA-GLIO stack. Both ship the same code and weights, signed end-to-end. Pilot partners have access today; public alpha opens Q4 2026.
pip install aurora-glio[org] aurora glio.org link \ --bench-run RUN-… \ --patient case.aurora
GLIO-ORG moves faster when the right people are in the room. Whether you carry a service line, a registry, or a few quiet weekends — there is a way in.
Sponsor GLIO-ORG for your unit. Co-design the surface, the audit log and the override semantics with the team that built it. Pilot sponsors keep a council seat for the duration.
Run a research question on GLIO-ORG. Federation means you can train across populations you cannot see alone. Whitepapers carry co-authorship, not acknowledgements.
GLIO-ORG ships starter tasks tagged 'good-first-issue' on the pilot repo. SDKs in Python, TypeScript and Rust at public alpha. MIT, no CLA.
AURORA is in private pilot today and opens to the world at public alpha in Q4 2026 under MIT. If you carry the weight of these diseases — as a clinician, scientist, builder, patient or advocate — there is a seat at the table.